There are many kinds of fantasy football leagues, and individual draft recommendations change with each new context. What doesn’t change is the overall strategy for how to come away with a successful draft experience.
American personas
A few weeks ago, Putting People First profiled a project by Claritas to create personas for Americana. Demographic data was compiled to come up with a few dozen different kinds of Americans and situate them in the geography of the nation. These personas might be used as a great initial step in a design inquiry.